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ORIGINAL ARTICLE
Year : 2016  |  Volume : 1  |  Issue : 2  |  Page : 120-124

Shelf life evaluation of Shirishavaleha: A preliminary study


Department of Rasa Shastra and Bhaishajya Kalpana including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
Dr. Harmeet Kaur
Department of Rasa Shastra and Bhaishajya Kalpana including Drug Research, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar - 361 008, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2468-838X.196099

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Context: Shelf life of the drug can be considered up to the period it gets deteriorated and does not get any alteration in its physicochemical state. Every product has definite shelf life, which depends on various physical, chemical, environmental, and biological factors. Ancient seers have clarified shelf life of various compound formulations. However, there is a need to revalidate and ascertain the shelf life of individual formulations by following parameters prevalent in respective scenario. Aim: To evaluate shelf life of Shirishavaleha prepared in the presence of water (SW) and Kanji (SK) as liquid media through accelerated stability study. Subjects and Methods: Physicochemical parameters were measured at 40°C ± 2°C temperature and 75% ±5% relative humidity. Analysis was repeated at intervals of 1, 3, and 6 months, and average 10% degradation of both the test drug samples was calculated and extrapolated to find the shelf life. Results: The sample prepared in the presence of Kanji (SK) showed more extractive values and sugar contents and found to have longer shelf life (2.6 years) than SW (1.4 years). Conclusion: Shirishavaleha prepared with Kanji (SK) is comparatively more stable than the sample prepared with water (SW).


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