• Users Online: 72
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2020  |  Volume : 5  |  Issue : 1  |  Page : 46-52

Influence of phytomelatonin on immune cell function in male golden hamsters


Department of Botany, Brahmananda Keshab Chandra College, Kolkata, West Bengal, India

Correspondence Address:
Dr. Dipanshu Kumar Vishwas
Department of Botany, Brahmananda Keshab Chandra College, 111/2 B.T. Road, Bonhooghly, Kolkata - 700 108, West Bengal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bjhs.bjhs_63_19

Rights and Permissions

BACKGROUND: An assortment of plant animal groups incorporates phytomelatonin, shows the similar pattern as in animals recommending its capacity can be closely resemble animals as in plants. AIMS AND OBJECTIVES: An in vivo research work needed to explore the impact of dietary phytomelatonin, i.e., the cabbage and carrot, on immune cell functions in a male rodent golden hamster (Mesocricetus auratus). MATERIALS AND METHODS: In this study, we examined the general immune response (spleen weight, total leukocyte count, and % lymphocyte), delayed type hypersensitivity (DTH) response, the blastogenic response of peripheral blood mononuclear cell (PBMC), splenocytes, and bone marrow mononuclear cell proliferation in terms of granulocyte macrophage colony forming unit (GM CFU) count, as an indicator of bone marrow macrophages. RESULTS: An increased circulatory melatonin level due to melatonin supplemented diet enhanced the total leukocyte count, % lymphocyte count, a proliferation of splenocytes, PBMCs, GM CFU count, % DTH response, and serum cytokine (interleukin 2 and interferon γ) production. CONCLUSION: A correlation study recommended that incited serum melatonin is emphatically corresponded with the improvement of the safe status of hamsters. In this way, our information infers that dietary melatonin may impact resistance on account of its high selectivity and sensitivity. Thus, it could be suggested that the dietary phytomelatonin might be one of the strong restorative procedures to enhance the immune responses for better well being of a person at its any age of life.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed70    
    Printed8    
    Emailed0    
    PDF Downloaded10    
    Comments [Add]    

Recommend this journal