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ABSTRACTS – PHD/POST DOCTORAL FELLOW
Year : 2020  |  Volume : 5  |  Issue : 3  |  Page : 25

Environmental exposure to microplastics: a scoping review on potential human health effects and knowledge gaps


1 Department of Community Health and Humanities, Faculty of Medicine, Memorial University St. John's NL A1B 3V6, Canada
2 Department of Civil Engineering, University of Calgary, 2500 University Drive NW, Calgary Alberta T2N 1N4, CANADA, Canada
3 Director Environmental Institute, Okruzna 784/42, 972 41 Kos, Slovak Republic

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2468-838X.303760

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Background: Microplastics are fast becoming a major global environmental contaminant. Little is known about the health effects of microplastic exposure to humans despite being omnipresent in all spheres of life and ecology. This scoping review explores the existing evidence of potential human health effects of microplastics and subsequent knowledge gaps. Methods: An electronic search of published articles in PubMed, Scopus, EMBASE, Cochrane databases, and Google Scholar was conducted, using a combination of subject headings and keywords for microplastics and human health effects. Documents only published in English between 2004 and March 2020 were included. A grey literature search was conducted following a comprehensive checklist in Google Scholar and the environmental organization websites. The initial search resulted in 17,043 published articles and grey literature. After a full review of published articles and their references, 125 publications were identified for further detailed review. Throughout the screening process, every document was reviewed by at least two of the researchers. Results: These articles indicate that human exposure to microplastics might occur through ingestion, inhalation, and dermal contact due to its presence in food, water, air, and consumer products. Microplastics exposure can cause particle toxicity through oxidative stress, inflammatory lesions, and increased uptake or translocation. Several studies have demonstrated the potentiality of metabolic disturbances, neurotoxicity, increased cancer risk, and reproductive toxicity in humans. Moreover, microplastics were found to release their constituent compounds and those adsorbed onto its surface in human tissues. Conclusion: Knowledge of microplastic toxicity on human health is still limited. Further research is needed to quantify the effect of microplastics on human health and pathogenesis.


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